Buy VIP Peptide

If you want to buy VIP peptide, it is of course important to know what it is. Vasoactive intestinal peptide (VIP, vasoactive intestinal polypeptide, PHM27) is a short peptidic hormone. This hormone is produced in the gut, pancreas and brain of most vertebrates, including humans. VIP binds to class II G protein-coupled receptors and is known to:

– Increase the breakdown of glycogen in the liver and muscles,

– Lowering blood pressure,

– Relaxation of smooth muscles throughout the gastrointestinal tract,

– Stimulating contraction of heart muscles (by increasing both heart rate and force of contractions),

– Stimulating the secretion of water in different parts of the gastrointestinal tract,

– Affecting vaginal lubrication,

– Regulate prolactin release,

– Protect cartilage,

– Protecting neurons against ischemia and oxidative stress,

– Influencing autonomic nerve function,

– Help synchronize the central nervous system (specifically neurons in the suprachiasmatic nucleus) with light signals to regulate circadian rhythm.

The benefit of improved intestinal barrier function should not be underestimated. This is because it is believed to be a contributing cause in the pathogenesis of inflammatory bowel disease. Compromised barrier function is thought to lead to an increase in antigenic material in the space between cells, where it is more likely to interact with immune cells and cause an inflammatory response. Thus, reducing the presentation of antigens to immune cells via improved barrier function due to VIP would reduce one of the first steps in the cascade of events leading to colitis and severe inflammatory bowel disease.

There are at least two ways that VIP affects lung function. In the first mechanism, VIP modulates pulmonary vascular remodeling in response to inflammation. It appears to have this effect through suppression of a peptide called NFAT. NFAT activates T cells leading to increased inflammation. Consistent with its role in modulating inflammation in other tissues, VIP appears to regulate inflammation by T cells in the lungs. This is a process that has so far been difficult to address in models of inflammation. In particular, NFAT suppression may play a very important role in preventing pulmonary fibrosis. This is the end stage of a number of inflammatory conditions such as COPD, sarcoidosis, and so on. Therefore, VIP may provide a very useful mechanism to prevent the type of end-stage lung disease that can only be cured by transplantation and that often results in serious morbidity and even death.

VIP also appears to inhibit smooth muscle proliferation in lung tissue. Smooth muscle cell proliferation is one of the long-term consequences of pneumonia. This consequence is a particular problem in bronchial asthma that has not been controlled for extended periods. There is hope that VIP will provide a mechanism to mitigate the effects of long-term inflammation from asthma.

There is also exceptional evidence that the vasodilatory effects of VIP, known to regulate blood pressure, may have a very potent effect in the pulmonary vasculature. Preliminary research shows that VIP significantly reduces blood pressure in the pulmonary artery. This in turn leads to increased cardiac output and improved venous oxygen saturation. More work remains to be done but there is considerable hope that VIP will provide a new modality for improving pulmonary function in primary vascular disease.

Research with VIP

Read more information about the research and effects of VIP peptide

Hazard statement VIP

Avoid contact with VIP’s eyes as this may cause irritation. In case of contact with eyes, rinse with water for several minutes and remove contact lenses if necessary.

View the Material Safety Datasheet of VIP peptide

Is it legal to buy VIP Peptide?

Yes, anyone over the age of 18 can buy VIP peptide because it is a research compound. Peptides are subject to various government rules and regulations. As a result, we are not permitted to present health claims or specify consumption methods. We supply VIP freeze-dried, with the choice between a spray bottle or a glass ampoule. This so that people can make their own choice about how they will research the peptide. This ensures shelf life: from the moment you mix the VIP Peptide in the spray bottle or glass ampoule with sterile water, it is effective and has a shelf life for 3 weeks.