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BPC-157

Price range: €49,95 through €409,95 Inclusief BTW

Order your desired quantity of BPC-157 and then select the way you want to receive it. We offer the choice between pre-packed in a glass ampoule or packed in a plastic tube with a spray bottle. In both cases we add sterile water to mix the BPC-157 powder.

Molecular formula: C62H98N15O22
Molecular mass: 1419.556 g/mol

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Discretely packed & directly available

SKU: BPC-157 Category:
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BPC-157 molecule
BPC-157 peptide product

Peptide Table of contents

Buy BPC-157

What is BPC-157

If you want to buy BPC-157, it is of course useful to know what it is. BPC 157 is a penta-decapeptide, consisting of 15 amino acids. It is a partial sequence of the body protective agent (BPC) discovered in and isolated from human gastric fluid. Animal studies have shown that it accelerates the healing of various wounds, including muscle, tendon and damaged ligaments. Additionally, BPC 157 has been shown to protect organs and aid in the prevention of stomach ulcers.

BPC-157 works systemically in the digestive system to combat leaky gut, irritable bowel syndrome (IBS), gastrointestinal cramps and Crohn’s disease. This peptide exhibits analgesic characteristics. Research has shown that it accelerates the healing of skin burns by increasing blood flow to damaged tissue. BPC-157 significantly accelerates reticulin and collagen formation, as well as angiogenesis, along with macrophage stimulation and fibroblast infiltration, which is a potential therapeutic tool in the treatment of wound healing.

BPC-157, abbreviated for Body Protection Compound-157, is a derivative of the body protection compound (BPC). BPC is a protein that naturally occurs in the human digestive system. It plays an important role in protecting the lining of the gastrointestinal tract from damage, promoting healing and stimulating blood vessel growth.

Effects of BPC-157

BPC-157 and wound healing

The natural function of BPC in the gastrointestinal tract (GI tract) is to maintain the integrity of the mucosal barrier that protects underlying tissues from the damaging effects of stomach acid, bile and other substances necessary for digestion and absorption of nutrients from food. At least part of this function is via the recruitment of fibroblasts. BPC-157 has a dose-dependent effect on fibroblast proliferation in culture and in vivo, causing cells to proliferate and migrate more quickly. Fibroblasts are essential for wound healing as they are responsible for depositing extracellular matrix proteins such as collagen, fibrin, elastin and more.

Vascular Growth and Collateralization
BPC-157 is a potent angiogenic factor, which increases the rate at which endothelial cells multiply and grow. Endothelial cells are cells that line blood vessels and play an important role in vascular growth. Research in rats shows that the peptide significantly increases the rate of collateral blood vessel growth during ischemia. Although this effect has been mainly observed in the gastrointestinal tract, there is evidence of similar benefits in cardiovascular, neurological and muscle tissues. This suggests that BPC-157 could be used as a therapy for stroke and heart attack. In addition, it can be used as a research tool to understand how to promote healing after ischemic injuries. Studies in chicken eggs suggest that at least part of the mechanism by which BPC-157 promotes vascular growth occurs via the stimulation of VEGFR2, a cell membrane receptor active in the nitric oxide signaling pathway. VEGFR2 is thought to play an important role in the growth, proliferation and longevity of endothelial cells.

BPC-157 and Tendon healing

Given BPC-157’s role in fibroblast recruitment and blood vessel growth, it is no surprise that BPC-157 has shown positive results in animal models of tendon, ligament, bone and other connective tissue injuries. Injuries to tendons and ligaments heal slowly, largely due to poor blood flow to these tissues. Poor blood supply slows the speed at which fibroblasts and other wound healing cells can reach the area of ​​the injury. This can be limiting in terms of the overall level of recovery. Both in vitro and in vivo studies in rat tendons have shown that BPC-157 promotes collateralization and increases fibroblast density in the event of injuries to tendons, ligaments and bones. This study states that BPC-157 is more effective than bFGF, EFG and VGF hormones in promoting healing in these tissues.

Experiments with FITC-phalloidin staining have shown that BPC-157 is a potent stimulator of F-actin formation in fibroblasts. F-actin is essential for cell structure and function, and plays an important role in cell migration. Western blotting analysis indicates that BPC-157 increases phosphorylation of paxillin and FAK proteins. These proteins are very critical proteins in the cell migration pathway.

Antioxidant Properties

Research in rats has shown that BPC-157 can neutralize certain markers of oxidative stress such as nitric oxide and malondialdehyde (MDA). This makes BPC-157 a very powerful antioxidant! Research shows that this can reduce the production of reactive oxygen species in the gastrointestinal tract. Research into whether modified lactococcus lactis bacteria can transport BPC-157 to the gastrointestinal tract shows that the bacteria dramatically increase levels of the peptide in cell culture.

BPC-157 and Side effects of medicines

Often the limiting factor when using medical drugs is the side effects. For example, NSAIDs such as ibuprofen cannot be used for long periods of time because they increase the risk of stomach bleeding and heart attack. The ability to counteract side effects while maintaining desired effects would enhance therapeutic benefits of various drugs. BPC-157 has been shown to counteract side effects of NSAIDs, medications used for psychiatric conditions, and some heart medications.

Read more information about research and effects of BPC-157

Hazard Statement BPC-157

Avoid contact with the eyes of BPC-157 as it may cause irritation. In case of contact with eyes, rinse with water for several minutes and remove contact lenses if necessary.

View the Material Safety Datasheet of BPC-157

Is it legal to buy BPC-157?

Yes, anyone over the age of 18 can buy BPC-157 because it is a research compound. Peptides are subject to various government rules and regulations. As a result, we are not permitted to present health claims or specify consumption methods. We supply BPC-157 freeze-dried, with the choice between a spray bottle or a glass ampoule. This so that people can make their own choice about how they will research the peptide. This ensures shelf life: from the moment you mix the BPC-157 in the spray bottle or glass ampoule with sterile water, it is effective and has a shelf life for 3 weeks.

Decide before 15:00 to buy BPC-157 so that you can have it at home tomorrow, order quickly!

Quantity

1 x 10 milligram BPC-157 powder with sterile water, 3 x 10 milligrams BPC-157 powder with sterile water, 5 x 10 milligrams BPC-157 powder with sterile water, 10 x 10 milligrams BPC-157 powder with sterile water, 25 x 10 milligrams BPC-157 powder with sterile water

Packaging

Spray bottle, Glass ampoule

Scientific information

IUPAC naam: (4S)-4-[(2-aminoacetyl)amino]-5-[(2S)-2-[(2S)-2-[(2S)-2-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-3-carboxy-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[2-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-5-oxopentanoic acid

Compound CID: 9941957

Isomeric SMILES: C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN

InChIKey: HEEWEZGQMLZMFE-RKGINYAYSA-N

InChI: InChI=1S/C62H98N16O22/c1-31(2)25-37(55(92)74-50(32(3)4)62(99)100)71-46(81)29-65-51(88)33(5)67-53(90)38(26-48(84)85)73-54(91)39(27-49(86)87)72-52(89)34(6)68-57(94)41-15-10-21-75(41)58(95)35(13-7-8-20-63)70-45(80)30-66-56(93)40-14-9-22-76(40)60(97)43-17-12-24-78(43)61(98)42-16-11-23-77(42)59(96)36(18-19-47(82)83)69-44(79)28-64/h31-43,50H,7-30,63-64H2,1-6H3,(H,65,88)(H,66,93)(H,67,90)(H,68,94)(H,69,79)(H,70,80)(H,71,81)(H,72,89)(H,73,91)(H,74,92)(H,82,83)(H,84,85)(H,86,87)(H,99,100)/t33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,50-/m0/s1

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All information on this site is of a general nature and is intended for your knowledge, understanding and educational purposes only. This information should not be construed as medical or other health advice relating to your specific health and medical condition. Our products are intended solely as research chemicals and may only be purchased by persons over the age of 18.

The strict use of research chemicals is only for in vitro testing and laboratory experiments. Introduction of any kind into humans or animals is strictly prohibited by law. Our products should only be handled by recognized, qualified professionals. This product is not a drug, food or cosmetic product and should not be marketed, misused or mislabeled as such.
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